Work on native support of MathML in WebKit has begun but is a long way from being ready to use. With MathJax, Readium will be able to render MathML, an important step towards Readium’s full EPUB 3 support. Additionally, MathJax offers zoom for accessibility and cut-and-paste of mathematical content.
The necessary code has been pulled into the master branch and, as of version 0.1.9, Readium displays math beautifully. You can find a sample here.
Thanks to Davide Cervone, MathJax’s Lead Developer, for his help in making MathJax work in Readium.